Masteron(Drostanolone Propionate) also known as drostanolone propionate) had formerly been a rare drug in the United States and was enjoyed principally by our European friends. This was due to never been produced in great quantity by Syntex and never being marketed in the United States. Masteron presently is available from various non-pharmaceutical suppliers. Many also make home-prepared injectables from powder provided by various sources.

Masteron is unaffected by the aromatase and 5alpha-reductase enzymes and therefore there are no issues with estrogen or with potentiation (increase of effect) in tissues such as the skin and prostate. In fact, Masteron is somewhat anti-estrogenic due to competing with estradiol at the estrogen receptor, while not itself activating the receptor, and perhaps by likewise competing with testosterone for the binding site of the aromatase enzyme, thus reducing conversion.

This is a benefit when only a moderate amount of aromatizing steroids are used and no other anti-estrogen is used. It is not, however, sufficient to fully deal with high doses of aromatizing steroids, or at least not with typical doses of Masteron; and is unnecessary when more effective anti-estrogens are employed.

Comment from Expert

Since estrogen is not an issue, side effects are generally mild with this steroid. As discussed earlier, gynecomastia, water retention, and high blood pressureare not a problem. Masteron is also not liver toxic, so there is little concern stress will be placed on this organ, even during longer cycles. The only real side effects would be from the basic androgenic properties of dihydrotestosterone. These includes oily skin, acne, body/facial hair growth, aggression and accelerated hair loss. Since this compound is already a synthetic DHT, Proscar would have no impact on the level of androgenic effects. Men with a receding hairline or those with a predisposition for baldness may therefore wish to stay away from Masteron completely, as the potent androgenic effect of this steroid can easily accelerate this condition.