Methandienone therapy is adjunctive to and not a replacement for conventional therapy. Duration of therapy will depend on the response of the condition and the appearance of adverse reactions. Therapy should be intermittent and no longer than necessary for optimal results.The usual initial adult dosage is 5 mg daily. For maintenance, 2.5 to 5 mg daily is usually sufficient. Intermittent therapy is recommended when Methandienone® is administered over long periods. For example, after six weeks of treatment, there should be an interval of two to four weeks before resuming therapy.Proper diet, particularly adequate protein intake, is required to assure the full anabolic benefits of Methandienone.Methandienone therapy is adjunctive to and not a replacement for conventional therapy. Duration of therapy will depend on the response of the condition and the appearance of adverse reactions. Therapy should be intermittent and no longer than necessary for optimal results.The usual initial adult dosage is 5 mg daily. For maintenance, 2.5 to 5 mg daily is usually sufficient. Intermittent therapy is recommended when Methandienone is administered over long periods. For example, after six weeks of treatment, there should be an interval of two to four weeks before resuming therapy.Proper diet, particularly adequate protein intake, is required to assure the full anabolic benefits of Methandienone.

Comment from Expert

In Males
Prepubertal : phallic enlargement; increased frequency of erections. Postpubertal : inhibition of testicular function, oligospermia; gynecomastia.

In Females:
Hirsutism ; male pattern baldness; deepening of the voice; clitoral enlargement. These changes are usually irreversible even after prompt discontinuance of therapy and are not prevented by concomitant use of estrogens. In addition, the following may occur: menstrual irregularities; masculinization of the fetus.